Callus Therapy Cream to help remove calluses naturally. Unlike many callus treatments that work by ‘burning’ the callus from the skin tissue, DiabEase Callus Therapy Cream contains an active % of Urea. This natural ingredient has the ability to gently exfoliate dry, cracked skin layers while deeply hydrating the skin and improving its ability to retain moisture. Dead Sea Minerals enhance skin softness. Vitamins E, A, and Green Tea nourish and provide natural anti-oxidant protection. Daily use on rough skin areas such as toes, elbows, and fingers may help prevent calluses from forming.